Pravara Institute of Medical Sciences


College of Biosciences and Technology , Loni

Centre For Biotehnology

College of Biosciences and Technology

The College of Biosciences and Technology was established in the year 2001 with a basic intention of facilitating the initiation of young students in the field of medical biotechnology, by imparting them quality education and further training them to take up either a research career or get recruited in the relevant industry or hone the skills to become successful entrepreneur.

Medical Biotechnology is a specialized disciplines dealing with the understanding & use of living cells or any biomaterial and its derivatives in health and diseases. It has an interdisciplinary approach that combines the knowledge of fundamental sciences including cell biology, biochemistry, genetics and many others for its application in the advancement of medicine in terms of disease diagnosis and development of therapeutics, neutraceutics etc. Therefore, it is considered to be the growing technology of the 21st century and has promising future to enhance the quality of life and environment.

Vision

To nurture and empower young, creative, and innovative minds in the field of biosciences and technology, fostering the development of highly skilled professionals who will make significant contributions to the advancement of human health, scientific discovery, and the betterment of society and the nation.

Mission

To be a centre of excellence in the field of biosciences and technology, offering need-based, high-quality education and training, fostering interdisciplinary collaboration, and conducting cutting-edge research to equip students and professionals with the skills, knowledge, and ethical foundation needed to drive innovation, address global healthcare challenges, particularly in underserved rural populations, and translate scientific discoveries into impactful and evidence-based healthcare solutions.



Objectives

  • To provide a comprehensive curriculum and cutting-edge training programs in the field of biosciences, and technology, ensuring students acquire the technical, practical, and ethical expertise required to excel in their fields and contribute to global healthcare challenges.
  • To create an inclusive and collaborative learning environment that brings together students and stakeholders from diverse academic backgrounds, promoting interdisciplinary research and innovation in the field of biosciences and technology to address societal challenges.
  • To establish state-of-the-art research facilities and foster a culture of creativity and critical thinking, enabling faculty and students to conduct pioneering research that drives technological advancements and scientific discoveries in biosciences.
  • To provide advanced training and practical experience for the next generation of biomedical scientists, with a focus on addressing critical healthcare issues, particularly in underserved rural populations, while instilling strong ethical principles and promoting evidence-based healthcare solutions.


The Faculty

The faculty of this Center is well trained and possesses relevant skills to conduct research and provide interdisciplinary training in fundamental areas at the forefront of medical biotechnology. We aim to cultivate a research environment that will also foster the advancement of the local and national biotechnology industry.

Curriculum Highlights

  • Core subjects: Cell Biology, Biochemistry, Microbiology includes Basics and Medical Microbiology
  • Biotechnology – Genetic Engineering, Molecular Biology, Immunology, Animal Tissue Culture, Basics of Bioinformatics, Industrial Biotechnology
  • Hands on practical in each subjects
  • Dissertation as integral part of curriculum
  • CBCS pattern offers elective subjects: Clinical research, Developmental biology, Human genetics
  • Credit system evaluates CGPA


Laboratories

The Center has the following laboratories with state-of-art equipment:
  1. General laboratory for microbiology and biochemistry studies
  2. Critical laboratory for molecular biology and genetic engineering studies
  3. Tissue culture laboratory for in vitro studies
  4. Bioinformatics laboratory - software package for sequence comparison, restriction enzyme site identification, primer design, and partial protein characterization.


Animal House

As part of creating the most suitable environment for encouraging and strengthening fundamental research, the University has built a fully equipped, modern Animal House with a floor area of 6,000 Sq.Ft. in strict accordance with the CPCSEA guidelines - the first one of its kind in Rural India.

The house is centrally air conditioned, humidified and maintained as totally sterile, with a capacity to hold at least 100 rodents and 100 mammalians. The House is also equipped with an Operation Theatre, experimental & clinical laboratory, separate breeding rooms, sick rooms, quarantine rooms etc. The animals are housed species wise in separate rooms in polycarbonate cages with supply of sterile water and automatic feeding and drainage system. Waste disposal is done through a special incinerator as per norms of Maharashtra Pollution Control Board.

RESEARCH AND DEVELOPMENT

Major Thrust Areas of Research
  1. Genomics
  2. Infectious Diseases
  3. Immunology
  4. Plant Biotechnology & Cellular Biology
  5. Drug designing & Bioinformatics
  6. Herbal & Food Sciences


ONGOING RESEARCH PROJECTS

  • Genetic analysis of HLA polymorphism in tribal and non tribal population of Maharashtra, India: A pilot study in collaboration with Drake University, USA
  • Evaluation of in vitro anticancer potential of some medicinal plants against various cancerous cell lines.
  • Biofilm formation ability of Pseudomonas aeruginosa isolated from various clinical specimens and anti-biofilm ability of Lactobacillus species against multidrug resistant Pseudomonas aeruginosa.
  • Plasmid Profile Analysis of Multidrug Resistant Pseudomonas aeruginosa isolated from rural tertiary care hospitals of Western Maharashtra.
  • In vitro inhibitory effect of G. glabra and T. cordifolia plant extracts on infectious Pathogenic organisms.
  • Assessing the effects of Donor variability on the quality and efficiency of Umbilical Cord derived Mesenchymal Stem Cells used for therapeutic applications.
  • Assessing the osteogenic potential of curcumin using stem cell differentiation assays.
  • In vitro evaluation of anti biofilm activity of crude natural extracts against multi-drug resistant Pseudomonas sps. obtained from pus sample.
  • Pharmacological evaluation of two medicinal plants of Ahmednagar district.


COLLABORATIONS

We have various Collaboration for Academic Programs and Research and Development Activities with the following organizations:

International : 1. Drake University, USA

National
  1. College of Agricultural Biotechnology, Loni
  2. DNA Labs- A Centre for Applied Sciences (DLCAS), Dehradun
  3. Rapture Biotech International Private Limited, Hyderabad
  4. BioNome, Bangaluru
  5. Padmashri Vikhe Patil College Of Arts Science & Commerce, Pravaranagar